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delta drosophila homolog-like 1;neoplasms;genes |
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DLK1 and neoplasms
ZHANG Yanli1, KANG Kaifu2
1.Department of Pathology, Guangdong Medical College，Zhanjiang Guangdong 524023; 2.Department
of Pathology，First People’s Hospital of Shunde, Nanfang Medical University, Foshan Guangdong 528300, China
Delta drosophila homolog-like 1 (DLK1) is a member of the epidermal growth factor family. As an important factor in regulation of cell differentiation, DLK1 has a wide rang of biological functions. Recently, many studies have shown that the expression of DLK1 is up-regulated in many tumor tissues, which may be involved in the occurrence and development of neoplasms through a variety of mechanisms.