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microRNA;diabetes;insulin |
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MicroRNA and diabetes
LIU Xiyu, LI Yijun, ZHOU Zhiguang
Department of Endocrinology, Second Xiangya Hospital; Institute of Metabolism
and Endocrinology, Central South University, Changsha 410011, China
MicroRNA is a class of short non-coding RNA that has important role in gene regulation. Recent studies have demonstrated that microRNA closely relates to insulin production, secretion, action, and pancreatic islet development, which is crucial for the pathogenesis of diabetes. It has been suggested that microRNA may have potential diagnostic and therapeutic applications in diabetes.