International Journal of Pathology and Clinical Me 2010, 30(1) 57- DOI:   10.3969/j.issn.16732588.2010.  ISSN: 1673-2588 CN: 43-1458/R
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Keywords
leptin;colorectal cancer;obesity
Authors
PubMed

Leptin and colorectal cancer

WANG Jingwen, JING Hongbiao, ZHENG Jinfeng

Department of Pathology, Jinan Military Region General Hospital，Jinan 250031, China

Abstract：

Obesity is recognized as a high risk factor for colorectal cancer. As the ob gene product, leptin is one of important adipokines and it mainly derives from adipocytes. Leptin is thought as a pivotal link between obesity and colorectal cancer. It has been demonstrated to play a crucial role in colorectal carcinogenesis and cancer development. The progress made in the research on leptin is beneficial to colorectal diagnosis and therapy.

Keywords： leptin;colorectal cancer;obesity  
Received  Revised  Online:  
DOI: 10.3969/j.issn.16732588.2010.
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Email: joanw90@126.com
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