神经生长因子对神经细胞生长及分化起重要作用，近年来的研究表明神经生长因子在胰腺癌

中的表达与胰腺癌疼痛、嗜神经生长有密切关系，并可能有预后提示作用。本文综述了神经生长因子在

胰腺癌的临床研究进展。

Nerve growth factor (NGF) is an important protein that induces the

differentiation and survival of particular target neurons. Recent studies have

demonstrated that NGF expression in pancreatic cancer is related to pancreatic pain and

perineural invasion of cancer cells, and it may even be a useful in prognostic prediction.

This article reviewed recent clinical advances of NGF in pancreatic cancer.

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