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国际病理 2006, 26(4) 21-358 DOI:
ISSN: 0412-1961 CN: 21-1139/TG |
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| 综述 |
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葡萄糖透析液与腹膜纤维化研究进展 |
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李建飞;刘伏友 |
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中南大学湘雅二医院肾内科,长沙 410011 |
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摘要:
湘雅二医院肾内科,长沙 410011) [摘要] 使用葡萄糖透析液进行腹膜透析透是治疗终末期肾脏病的有效措施之一。但近年来大量临床研究发现,透析液中葡萄糖对腹膜的结构和功能有重要影响,导致腹膜纤维化,超滤失败,最终放弃腹膜透析。了解透析液中葡萄糖对腹膜的影响及潜在的治疗策略具有十分重要的意义。 |
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关键词:
葡萄糖
葡萄糖降解产物
糖基化终末产物
腹膜纤维化
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Advance of glucose-based dialysate and peritoneal fibrosis |
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LI Jian-fei, LIU Fu-you
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Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011, China
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Abstract:
Peritoneal dialysis(PD) using glucose-based dialysate is one of the effective treatment for patients with end-stage renal disease.But many clinical investigations show that exposure of the peritoneal membrane to high glucose concentrations contributes to both structural and functional changes in the dialyzed peritoneal membrane. In the end,patients drop out from PD due to peritoneal fibrosisand ultrafiltration failure over time on dialysis. So it is very important to know adverse effects of glucose in PD solutions and potential therapeutic interventions. |
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Keywords:
glucose
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收稿日期 2006-03-10 修回日期 2006-06-22 网络版发布日期 |
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DOI: |
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| 1.杜新,赖学莉;黄颂敏.脂筏蛋白与Cb1相关蛋白在葡萄糖转运中的信号转导机制[J]. 国际病理, 2006,26(2): 12-138 |
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