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国际病理 2009, 29(4) 357-360 DOI:
ISSN: 0412-1961 CN: 21-1139/TG |
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| 综述 |
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肿瘤微环境和口腔癌相关成纤维细胞
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孙鑫综述 何永文审校 |
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昆明医学院附属口腔医院， 昆明 650031 |
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摘要：
肿瘤微环境是一个有其自身特点的系统，它有别于正常细胞和其周围组织形成的环境。癌相关成纤维细胞(carcinoma-associated fibroblasts,CAFs)是肿瘤微环境中最主要的宿主细胞。口腔肿瘤微环境中的成纤维细胞有别于口腔正常成纤维细胞，在口腔肿瘤的发生、发展及治疗中起着重要作用。 |
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关键词：
肿瘤微环境
癌相关成纤维细胞
口腔癌
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Tumor microenvironment and oral carcinoma-associated fibroblasts |
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SUN Xin， HE Yongwen
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Affiliated Stomatological Hospital of Kunming Medical College, Kunming 650031, China
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Abstract:
The tumor microenvironment is a system with different characteristics from the normal tissue microenvironment. Carcinoma-associated fibroblasts (CAFs) are the most important cells in tumor microenvironment. Characteristics of the fibroblasts in the oral cancer microenvironment are different from the normal fibroblast cells. The fibroblasts in the oral cancer microenvironment play an important role in cancerogenesis, development, and metastasis. |
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Keywords:
tumor microenvironment
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收稿日期 2009-06-07 修回日期 2009-07-10 网络版发布日期 |
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DOI: |
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基金项目:
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通讯作者: 何永文 |
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| 本刊中的类似文章 |
| 1．胡多沙;曹亚.肿瘤微环境中的免疫效应抑制[J]. 国际病理, 2007,27(2): 4-111 |
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