Home
|
About Journal
|
Editorial Board
|
Instruction
|
Subscribe
|
News
|
Archive
|
Advertisement
|
Contacts Us
|
中文
Office
Online Submission
Manuscript Tracking
Peer Review
Editor Work
Office Work
Editor-in-chief
Member
Username
Password
Register
Quick Search
Advanced Search
Visitors
Total visitors:
Now online:
Links
中国期刊网
万方数据
Current Issue
Latest issue
2008 Vol.28 (Number 5)
Oct. 28, 2008
论著
综述
论著
1
XING Xiao-ming, SUN Ling-ling, RAN Wen-wen and ZHU Zong-ling
Recombinant human epidermal growth factor accelerates the
recovery of the toxic acute tubular necrosis
ObjectiveTo study whether the domestic recombinant human epidermal growth factor (rhEGF) accelerates the recovery of gentamicin (GM)-induced toxic acute tubular necrosis in rats.Methods Mature Wistar rats were randomly divided into 3 gr...
2008 Vol. 28 (5): 369-375 [
Abstract
] (
11
) [
HTML
0KB] [
HTML
0KB] [
PDF
1999KB ](
15
)
2
ZHOU Zhi-ping, , LI Qiang, , YANG Xiao-su, TAN Li-ming, WANG Ai-yue and YANG Guo-shuai
Expressions of HIF-1α and MMP-2 in the perihematoma after
intracerebral hemorrhage in rats
ObjectiveTo observe the expressions of hypoxia-inducible factor (HIF)-1α and matrix metalloproteinases (MMP)-2 in the perihematoma after ICH in rats and to study the relation between HIF-1α and MMP-2.MethodsFifty healthy SD rats were ...
2008 Vol. 28 (5): 376-380 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
943KB ](
13
)
4
WANG Ling-ling and YAO Gen-you
Reg4 expression and signification in gastrointestinal carcinoma
WANG Ling-ling, YAO Gen-you
Reg4 is a member of Regenerating family, which is located in 1p12-13.1, and expresses a secreted protein composed of 158 amino acid. Reg4 protein is constitutively expressed in parietal cells of the gastric mucosa and the neuronendocri...
2008 Vol. 28 (5): 386-389 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
773KB ](
12
)
综述
3
XU Jia-ming LI Xue-nong
Advances in proteomics related to tumor metastasis of digestive system
Proteomics has already become one of the key methods and made great progress in the research of tumour metastasis. By means of proteomics technique, metastasis-related proteins can be identified to illustrate the molecular mechanism of ...
2008 Vol. 28 (5): 381-385 [
Abstract
] (
12
) [
HTML
0KB] [
HTML
0KB] [
PDF
784KB ](
11
)
5
YANG Qiong, LI Shu-guang and YE Zai-yuan
Advances in anti-angiogenesis therapy in gastric cancer
Angiogenesis was thought to be a key event in the growth and metastasis of gastric cancer. When tumor grows to certain extent, new vasculature was needed to access to provide nutrition and carry away the waste. Researches into angiogene...
2008 Vol. 28 (5): 390-394 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
794KB ](
8
)
6
QIU Xiu-qin and SHI Wei
Progression of tumor suppressor gene methylation
related to gastric cancer
DNA methylation is a kind of epigenetic modification in human genome. DNA methylation is one of the regulators on the expression of genes .The expression of genes can be “silenced” by hypermethylation of the tumor suppressor genes, wh...
2008 Vol. 28 (5): 395-398 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
775KB ](
10
)
7
MA Tie-jun and ZHOU Qi-quan
Neutriphil elastase in cancer development and progression
The neutrophil elastase is an important noxious molecule secreted by neutrophils. Reserches have found that it can promote the tumor cell proliferation, spread and metustasis. It plays a significant role in cancer development, progressi...
2008 Vol. 28 (5): 399-402 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
773KB ](
9
)
8
CHEN Wei-qiong , , YANG Hui-ling and
Progression of anticancer machanism of resveratrol
Resveratrol, a phytoalexin found in grapes and other food products, has been demonstrated to be a green anticancer drug. Recently, resveratrol was shown to have cancer chemopreventive activity in vivo and in vitro, and its cancer chemop...
2008 Vol. 28 (5): 403-407 [
Abstract
] (
12
) [
HTML
0KB] [
HTML
0KB] [
PDF
791KB ](
9
)
9
LI Min, WANG Ling-ling, JIAO Xue-juan and WANG Bo
Volume-regulated chloride channels and neoplasm
Volume-regulated chloride channels play a significant role in the cell volume regulation, proliferation and apoptosis in many cell types. The molecular identification, however, has not been determined. In recent years, it has been reali...
2008 Vol. 28 (5): 408-411 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
775KB ](
10
)
10
JIANG Sha-li LUO Zhao-yang
EphA2 and tumor
Receptor tyrosine kinases (RTKs) are involved in cellular growth，differentiation, embryonic development，and intracellular signalling pathways, and possess important physiological functions. EphA2 belongs to Eph receptor tyrosine kinas...
2008 Vol. 28 (5): 412-415 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
781KB ](
8
)
11
SHANG Xiao-yuYANG Xue-feng
Leptin and tumorigenesis
Leptin is a 146-aa peptide hormone that is produced mainly by adipose tissue, and encoded by obese(ob) gene . Leptin activates several singal transduction pathways, can regulate ingestion and energy consumption, and enhance cell growth ...
2008 Vol. 28 (5): 416-420 [
Abstract
] (
11
) [
HTML
0KB] [
HTML
0KB] [
PDF
785KB ](
8
)
12
WANG Xiao-wei, MAO-YING Qi-liang and WANG Yan-qing
Progress in the study of peripheral mechanism of bone cancer pain
Cancer pain is very common in patients with late stage cancer, and has the most significant impact on the life quality of patients. The recently published animal models of pain induced by localized and progressive bone cancer have allow...
2008 Vol. 28 (5): 421-424 [
Abstract
] (
11
) [
HTML
0KB] [
HTML
0KB] [
PDF
778KB ](
8
)
13
LIU JinLI Gui-xin
Cyclooxygenase-2 and the development of breast cancer
Cyclooxygenase (COX) is the rate-limiting enzmyme for the conversion of arachidonic acid into prostaglandin (PG). COX-2 expression is associated with generation, development and prognosis of breast cancer. It may increase motility and i...
2008 Vol. 28 (5): 425-428 [
Abstract
] (
11
) [
HTML
0KB] [
HTML
0KB] [
PDF
775KB ](
8
)
14
TANG Shuai and WEN Ge-bo
Membrane initiated estrogen signaling pathway in breast cancer
Estrogen-triggered signaling cascades via a plasma membrane-associated form of the receptor，can lead both to altered functions of proteins in the cytoplasm and to regulation of gene expression,which referred as nongenomic actions of es...
2008 Vol. 28 (5): 429-432 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
833KB ](
7
)
15
LIU Jing and GUO Wen-jun
Advances in lung cancer stem cells
Tumors come of stem cells, cancer stem cells are the source of metastasis and recurrent of tumors. The researches of lung cancer stem cells relatively fall behind and have not got received data about lung cancer stem cells, but animal ...
2008 Vol. 28 (5): 433-435 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
761KB ](
8
)
16
MING Jia and LIU Liang-ming
Relation between gap junction and the modulation of vasomotor function
Gap junction (GJ) is thought as the cell membrane channel which comprises of connexins and allows electronic signal,ions,small metabolites (<1 kD), and second messengers to translocate from cell to cell. GJ not only takes an importan...
2008 Vol. 28 (5): 436-442 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
871KB ](
7
)
17
CHEN Chen, ZHAO Shui-ping and XU Dan-yan
Soluble epoxide hydrolase and cardiovascular diseases
Soluble epoxide hydrolase （sEH）which is widely distributed in mammalian tissues, hydrates epoxyeicosatrienoic acid (EETs) into their corresponding less effective substances. Since sEH is closely related to hypertension, end-organ dama...
2008 Vol. 28 (5): 443-446 [
Abstract
] (
10
) [
HTML
0KB] [
HTML
0KB] [
PDF
777KB ](
7
)
18
ZHOU Ling-zhi WU Jie
Progression of adipocyte fatty acid binding protein
Fatty acid-binding proteins (FABP) belong to a family of low-molecular-weight cytoplasmic protein, and adipocyte fatty acid binding protein (A-FABP/ aP2) is one of the members of the family. A-FABP binds saturated or unsaturated long-ch...
2008 Vol. 28 (5): 447-451 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
784KB ](
7
)
19
DONG Yuan-yuan and XIAO Xin-hua
Effect of adiponectin on diabetic macro-angiopathy
Adiponectin (APN) is an adipocyte secreting cytokine, which exerts anti-inflammatory, anti-diabetic,and anti-atherosclerotic effects via combining with adiponectin receptor-l and 2. The serum adiponectin concentration is similar betwe...
2008 Vol. 28 (5): 452-455 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
774KB ](
8
)
20
KUANG Xin-yu and HUANG Wen-yan
TRPC6 and kidney disease
Transient receptor potential channel (TRPC), which is one of the members of transient receptor potential (TRP) channel, is a nonselective ion channel. It generally distributes in human body, including nervous system, immune system, kid...
2008 Vol. 28 (5): 456-460 [
Abstract
] (
9
) [
HTML
0KB] [
HTML
0KB] [
PDF
789KB ](
6
)
Copyright © 2007 Editorial Office of Internationa Journal of Pathology and Clinical Medicine
Support by
Beijing Magtech Co.ltd
, E-mail:
support@magtech.com.cn
